Simon Grandjean Lapierre

Dr. Simon Grandjean Lapierre is an Associate Clinical Professor in the Department of Microbiology, Infectious Diseases and Immunology at the University of Montreal, with a concurrent appointment as a Clinician Researcher at the Research Center of the University Hospital Center of the University of Montreal (CRCHUM). His translational research program focuses on tuberculosis control in Canada and Madagascar through interdisciplinary approaches.

Education includes:

• MD, MSc, FRCPC from University of Montreal (Internal Medicine, Infectious Diseases, Medical Microbiology)
• Graduate training in International Health from University of Sherbrooke
• Genomics applied to mycobacteria from Aix-Marseille University
• Postdoctoral training on TB control technologies in Madagascar

Research integrates molecular diagnostics, bacterial genomics, and digital innovations:

• Themes: Molecular diagnosis/genomics, AI/acoustic epidemiology
• Topics: TB molecular epidemiology, clinical diagnostics, cough-based digital monitoring, and global health implementation

Laboratory capabilities include BSL-3 facilities and CITADEL acoustic analysis platform.

Publications (2019-2021) demonstrate consistent focus on TB innovation: 67% feature Madagascar fieldwork, 83% incorporate genomic/digital technologies, and 100% address diagnostics or resistance. Primary methodologies include cost-effectiveness analysis (33%), diagnostic validation (33%), and mixed-methods approaches (17%).

Leads laboratory team at CRCHUM:

• Floriane Point: Research Assistant (BSL-3/NGS Platform)
• Dominique Doré: Research Assistant (Acoustic Epidemiology/CITADEL)