Signe Danielsen

Signe Danielsen is an Adjunct Associate Professor at the Norwegian University of Science and Technology (NTNU), affiliated with the Faculty of Medicine and Health Sciences and the Department of Clinical and Molecular Medicine. Her research focuses on radiation therapy optimization, proton therapy, brachytherapy, and biopolymer-based gene delivery systems.

• Education: PhD in Physics (2004), NTNU
• Teaching: Courses on ionizing radiation mechanisms, clinical physics for radiotherapy

Her recent work includes in silico adaptation of proton therapy for head and neck cancer, synthetic CT generation for prostate cancer planning, and patient-reported outcome assessments in radiotherapy. She has contributed to understanding DNA-chitosan complexation and its applications in gene delivery.

Key research areas include:

• Radiation oncology and medical physics
• Adaptive and image-guided therapies
• Molecular biophysics of polyelectrolyte complexes
• Clinical trial dosimetry

Her academic output spans high-impact journals like International Journal of Radiation Oncology, Acta Oncologica, and Biomacromolecules, with collaborations across oncology, physics, and nursing disciplines.