Shobbir Hussain

Shobbir Hussain is an Associate Professor and Senior Lecturer in the Department of Life Sciences at the University of Bath. He holds a PhD in Human Genetics from King’s College London and completed postdoctoral training at the University of Cambridge. His research focuses on understanding how mRNA transcriptome plasticity influences neurodevelopmental disorders and learning difficulties, employing next-generation sequencing and transgenic models for in vivo studies.

Education:

• PhD in Human Genetics, King’s College London
• Postdoctoral training at the University of Cambridge

Research Interests: Dr. Hussain’s work centers on molecular investigations of mRNA transcriptome dynamics, particularly in neurodevelopmental disorders. His laboratory develops and applies advanced sequencing techniques, such as Nanopore sequencing, and utilizes genome-edited models to study biological outcomes. Key areas include RNA methylation mechanisms, epitranscriptomics, and the functional implications of transcriptomic variations.

His research has been supported by grants from the Biotechnology and Biological Sciences Research Council, The Wellcome Trust, and The Royal Society. Notable projects include studies on the functions of extra-nuclear splicing regulators, epitranscriptome characterization using catalysis-dependent RIPseq, and the development of FICC-Seq for methyl-5-uridine profiling.

Advising and Grants: Dr. Hussain has supervised one documented research student. His grants span from 2015 to 2025, addressing topics such as neuronal connectivity and mRNA methylation patterns.

Labs and Teams: His laboratory at the University of Bath specializes in cutting-edge sequencing technologies and in vivo model systems to explore transcriptomic and epigenetic mechanisms underlying neurological conditions.