معرفی
Shetuan Zhang is a Professor in the Department of Biomedical and Molecular Sciences at Queen's University, affiliated with the School of Medicine and Faculty of Health Sciences. His research focuses on ion channel function, particularly the HERG potassium channel's role in cardiac arrhythmias and sudden cardiac death. He holds cross appointments in the Translational Institute of Medicine (TIME) and collaborates widely on drug safety and channelopathies.
Research interests include structural basis of ion channels, drug-channel interactions, and potassium channel physiology. Projects investigate mechanisms of drug-induced HERG block, hypokalemia effects, and autoimmune impacts on ion channels. His lab employs electrophysiology, molecular biology, and animal models to study channelopathies and arrhythmia prevention.
Recent work highlights opioid and amiodarone effects on HERG channels, emphasizing translational implications for cardiac safety. Zhang's publications span 1995 to 2024, with notable contributions on channel regulation, drug interactions, and protease-mediated damage. His team explores therapies targeting channel stability to treat Long QT Syndrome and arrhythmias.
