معرفی
Shekh Sabir is a Research Fellow in the Medicinal Chemistry department at Monash University. His research focuses on developing novel compounds to combat bacterial infections through quorum sensing inhibition and biofilm disruption.
- 2017–2023 Research Output: 13 publications including 10 articles and 3 review papers.
- Collaborations: Active partnerships with researchers across Australia and international institutions.
Research Interests: Sabir's work primarily targets Pseudomonas aeruginosa, a major pathogen in antibiotic resistance. His research spans:
- Designing quinazolinone and dihydropyrrol-2-one analogues
- Quorum sensing inhibition mechanisms
- Biofilm disruption strategies
- Organic synthesis of antimicrobial compounds
- Addressing antibiotic resistance through alternative therapies
- Structure-activity relationship studies
Recent Publication Trends: His 2023–2025 work emphasizes:
- Cationic dihydropyrrol-2-ones as dual-action agents
- Combinations of ascorbic acid with furanones for enhanced biofilm disruption
- Disulfide-based quorum sensing inhibitors
- Halogenated compounds targeting pyocyanin biosynthesis
Technical Expertise: Sabir specializes in synthetic methodologies including Beckmann rearrangement, aziridination, and hydroxylamine reagent applications.
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