
معرفی
Seth Horne is a Professor in the Department of Chemistry at the University of Pittsburgh, affiliated with the Dietrich School of Arts and Sciences. His research focuses on bioorganic chemistry and protein engineering, with emphasis on synthetic modifications of peptides and proteins to study folding behavior, develop therapeutics, and create bio-inspired materials. The Horne Laboratory’s interdisciplinary work spans organic chemistry, biophysics, structural biology, and materials science.
Key research themes include controlling peptide folding for drug design, designing self-assembling supramolecular systems, and exploring protein backbone modifications to enhance stability and functionality. Notable achievements include the development of proteomimetic analogues and methods to study protein energetics and structure. His lab is actively involved in mentoring graduate students, with ongoing projects in protein backbone engineering and functional materials.
- Awards: Chancellor's Distinguished Research Award (2016), NSF CAREER Award (2012), and Goldwater Scholarship (1999).
- Grants: Extensive funding from NSF, NIH, and institutional programs supports his research on synthetic proteins and biomaterials.
- Labs/Teams: Horne Lab focuses on chemical protein synthesis, supramolecular assembly, and biophysical characterization of engineered proteins.





