Serdar Yavuzyigitoglu

Serdar Yavuzyigitoglu is a Researcher in the Department of Ophthalmology at Erasmus University Medical Center (Erasmus MC), Rotterdam, specializing in uveal melanoma research. His work spans molecular diagnostics, treatment outcomes, and epidemiological studies of this rare ocular malignancy.

His primary research focuses on genetic drivers of uveal melanoma (particularly BAP1 and SF3B1 mutations), metastatic progression patterns, and comparative effectiveness of radiation therapies. He investigates how chromosomal aberrations like 8q gain influence prognosis, examines global incidence patterns correlated with pigmentation factors, and analyzes 30-year treatment trends in Dutch patient cohorts. His research bridges molecular biology with clinical outcomes to improve risk stratification and therapeutic decision-making.

Analysis of his 15 most recent publications reveals consistent emphasis on metastatic uveal melanoma biology, with growing integration of genomic data into clinical frameworks. His work demonstrates strong epidemiological rigor in population studies while advancing molecular understanding of treatment resistance mechanisms, particularly in liver metastasis contexts.

Yavuzyigitoglu actively collaborates with the Rotterdam Ocular Melanoma Study Group (ROMS), contributing to multi-center investigations that have generated significant clinical insights published in high-impact journals including Scientific Reports, Ophthalmology Science, and Cancers.