Sebastian Walther

Prof. Sebastian Walther is a Professor and Head of the Department of Psychiatry, Psychosomatics and Psychotherapy at the University Hospital of Psychiatry and Psychotherapy, University of Bern. His primary affiliation is with the Medical Faculty, focusing on psychiatric research and clinical practice. His work integrates neuroimaging, neuromodulation, and behavioral experiments to study motor behavior deficits in schizophrenia, depression, and affective disorders.

Research interests include psychomotor slowing, nonverbal communication deficits, personal space regulation in psychosis, and the neurobiological basis of psychiatric symptoms. He leads projects on gesture analysis in schizophrenia, pharmacokinetic modeling during pregnancy, and smartphone-based mental health metrics. Notable contributions include studies on CYP1A2 genotype effects on drug metabolism and the neural correlates of paranoia.

Publications (2023–2025) emphasize transdiagnostic motor dysfunction, electroconvulsive therapy neuroplasticity, and personalized suicide prevention programs like ASSIP flex. His work spans clinical trials (e.g., repetitive TMS for schizophrenia) and translational research linking brain imaging to symptom severity. He collaborates internationally on diffusion MRI harmonization and motor cortex physiology studies.

Current initiatives include investigating natural light and activity effects on mood, and entrepreneurship among chemistry students in Germany. His research aims to improve diagnostic tools and therapeutic interventions targeting motor and cognitive disturbances in psychiatric disorders.