Saurabh Sinha

Saurabh Sinha is the Wallace H. Coulter Distinguished Chair in Biomedical Engineering and an Adjunct Professor at Georgia Institute of Technology's School of Computational Science and Engineering. His research focuses on computational methods to decipher how DNA encodes biological properties, particularly through regulatory DNA analysis using machine learning and statistical physics. He co-leads the NIH-funded KnowEng data platform and the NSF AI Institute for Chemical Synthesis (MoleculeMaker.org).

• Roles: Adjunct Professor (Biomedical Engineering), Wallace H. Coulter Chair
• Affiliations: Georgia Tech's School of Computational Science and Engineering, NSF AI Institute for Chemical Synthesis

Research interests include regulatory DNA's role in embryonic development, cancer progression, and social behavior. Recent work addresses multi-omics integration, spatial transcriptomics, and AI-driven causal inference in omics data. Tools developed include CellSP, InSTAnT, and KnowEng.

His work bridges computational methods and biological systems, with applications in precision medicine and synthetic biology. Projects include identifying non-coding DNA variants linked to disease and developing algorithms for tumor microenvironment analysis.

• Awards: Wallace H. Coulter Distinguished Chair appointment

Advising and grants: Led over 30 researchers in KnowEng; co-PI of NSF AI Institute. Collaborations span genomics, oncology, and systems biology. Current efforts focus on spatial omics and multi-omics integration to understand disease mechanisms.