معرفی
Saskia Trump is a Researcher in Molecular Epidemiology at Charité Universitätsmedizin Berlin and the Berlin Institute of Health, affiliated with Irina Lehmann's Lab. Her work bridges epigenetics, environmental health, and molecular biology, focusing on how exposures like air pollution, toxins, and viral infections drive diseases such as asthma, COVID-19, hypertension, and cancer through mechanisms like DNA methylation and immune dysregulation.
Her research interests include:
- Epigenetic Regulation: DNA methylation changes in response to environmental stressors (e.g., air pollution, maternal smoking) and their role in asthma, allergies, and transgenerational health effects.
- Viral Pathogenesis: Host-pathogen interactions in COVID-19, including epigenetic memory, immune responses, and comorbidities like hypertension.
- Cancer Metabolism: Aryl hydrocarbon receptor (AHR) signaling, tryptophan catabolism, and metabolic reprogramming in glioblastoma and other cancers.
Trump's recent articles (2022–2025) emphasize SARS-CoV-2 epigenetics, pediatric health, and environmental toxicology. Trends show a strong focus on single-cell genomics, DNA methylation sequencing, and translational applications for respiratory and metabolic diseases.
She collaborates extensively across disciplines, contributing to studies on cystic fibrosis, glioblastoma, and childhood asthma. Current lab projects explore:
- Long-term epigenetic effects of COVID-19 in airway cells.
- Impact of moderate air pollution on respiratory epigenomes.
- Metabolic-immune crosstalk in cancer progression.
