Sandeep Silawal

Sandeep Silawal is a Research Fellow at the Institute of Anatomy and Cell Biology, Paracelsus Medical University, with active roles in Nuremberg and Salzburg. His work focuses on the role of complement proteins in diseases such as osteoarthritis, SARS-CoV-2 infection, and developmental anomalies.

• Active projects since 2023, 2020, and 2017 explore complement regulation in lung/heart tissue during viral infections, osteoarthritis pathogenesis, and muscle/vascular anatomical variations.
• He supervises student research on topics like complement interactions in synovial fibroblasts and osteoarthritis signaling pathways.

Research Interests

Sandeep investigates the complement system's role in inflammatory and degenerative diseases, with recent studies on:

• SARS-CoV-2: Complement regulation in infected lungs and synovial fibroblasts.
• Osteoarthritis: Interactions between complement proteins (C5/C5a), cathepsin D, and prolactin in chondrocytes.
• Anatomical Variations: Muscle anomalies (e.g., cleidocervical muscle) and vascular malformations.

Email

• sandeep.silawal@pmu.ac.at