معرفی
Ryley Parrish serves as an Assistant Professor in the Department of Cell Biology & Physiology within the College of Life Sciences at Brigham Young University (BYU), where he maintains a primary appointment in the Neuroscience program. His laboratory investigates fundamental mechanisms underlying neurological disorders with clinical significance.
Dr. Parrish's research program focuses on:
- Endogenous inhibitory restraint mechanisms in seizure termination
- Role of cortical spreading depression in both seizure cessation and migraine pathophysiology
- Neurobiological basis of pharmacoresistant status epilepticus
- Spontaneous seizure propagation dynamics in neural networks
The Parrish Lab employs an integrated methodological approach combining in vitro and in vivo electrophysiology, optogenetic circuit manipulation, live neural network imaging, and computational modeling to dissect complex seizure phenomena. This multidisciplinary strategy enables comprehensive investigation of neural circuit behaviors during pathological states.
Dr. Parrish directs an active research laboratory dedicated to advancing epilepsy therapeutics through mechanistic understanding. The lab maintains strong technical infrastructure for neurophysiological experimentation and computational analysis, with findings contributing to both basic neuroscience and translational applications. Further details are available at the Parrish Lab website.
