Rui Wang

Rui Wang is a Research Fellow in the Department of Immunobiology at Yale School of Medicine, Yale University. Their research focuses on the intersection of immunology, microbiome dynamics, and liver diseases, particularly autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis. Wang’s work explores mechanisms of disease pathogenesis, therapeutic interventions, and biomarker discovery.

Key research themes include gut microbiome influences on liver immunology, the role of epigenetic and metabolic reprogramming in disease progression, and the application of bacteriophage therapy for antibiotic-resistant infections. Recent studies highlight innovations in corticosteroid tapering schemes, microbiota-derived metabolites (e.g., butyrate), and itaconate’s immunomodulatory effects.

Publications span translational immunology, microbiome analysis, and preclinical phage therapy models. Their findings contribute to personalized treatment strategies and understanding host-microbe interactions in chronic liver disorders.

Wang collaborates on trans-ethnic genetic analyses and has developed novel phage-based approaches targeting multidrug-resistant bacteria, including Acinetobacter baumannii and Klebsiella pneumoniae.