Roy M. Long

Roy M. Long, PhD, serves as Professor and Assistant Dean for Graduate Recruitment in the Department of Microbiology & Immunology at the Medical College of Wisconsin. His research utilizes S. cerevisiae as a model system to investigate fundamental mechanisms of RNA localization and its role in post-transcriptional gene regulation.

His educational background includes:

• PhD in Biological Chemistry from Pennsylvania State University (1994)

Dr. Long's laboratory employs genetic, biochemical, and cell biological approaches to dissect RNA transport mechanisms, with seminal contributions to understanding the She protein complex (She1p/Myo4p, She2p, She3p) and actin cytoskeleton dynamics in ASH1 mRNA localization. His work demonstrates how RNA-binding proteins recognize cis-acting elements and how molecular reorganization enables mRNA anchoring at cellular poles, establishing conserved principles applicable to higher eukaryotes.

Analysis of his 12 publications from 2003-2017 reveals sustained focus on RNA transport mechanisms in yeast, evolving from foundational studies of ASH1 mRNA localization to broader investigations of ribosome biogenesis, mitochondrial protein import, and nucleolar stress responses. His methodologies consistently integrate advanced microscopy with molecular genetics to track RNA dynamics in living cells.

No scientific awards were documented in the provided materials.

As Assistant Dean for Graduate Recruitment, Dr. Long oversees graduate student admissions and mentoring programs. His laboratory operations in BSB 252 involve collaborative research teams developing techniques for in vivo RNA tracking and biochemical analysis of RNA-protein complexes, supported by sustained research funding evident in his publication record.

His research group maintains active investigation of mRNA transport machinery using yeast genetics, with ongoing work examining molecular reorganization events during mRNA anchoring and exploring conservation of mechanisms in developmental contexts.