معرفی
Ronghu Wu is a Professor in the School of Chemistry and Biochemistry at the Georgia Institute of Technology, where he leads the Wu Lab focused on cutting-edge mass spectrometry-based proteomics. His research integrates analytical chemistry, chemical biology, and biomedical sciences to understand protein post-translational modifications (PTMs), cell signaling, and cancer metabolism.
Education
- M.S. and Ph.D. in Analytical Chemistry, University of Science and Technology of China
- Postdoctoral Fellow, Harvard Medical School (2009–2012)
Research Interests
Professor Wu’s group develops and applies novel liquid chromatography–mass spectrometry (LC-MS) strategies to investigate protein PTMs—especially glycosylation—protein dynamics, and their roles in disease. A major focus is on quantitative glycoproteomics to map the cell-surface glycoproteome (surfaceome) and to elucidate how aberrant glycosylation drives cancer metastasis and metabolic reprogramming. Complementary projects explore how protein modifications regulate cell signaling, stress responses, and therapeutic drug effects, with the ultimate goal of identifying new biomarkers and drug targets for personalized medicine.
Scientific Awards
- ASMS Research Award (2016)
- NSF CAREER Award (2015)
- Blanchard Assistant Professorship (2014)
- Alexander von Humboldt Research Fellowship (2002–2004)
Grants & Funding
His research has been continuously supported by the U.S. National Science Foundation (NSF CAREER) and other competitive grants, enabling the development of innovative chemoproteomic tools and their application to clinically relevant problems.
Laboratory & Team
Professor Wu directs the Wu Lab located in the Engineering Biosystems Building (EBB 4011) at Georgia Tech. The multidisciplinary team comprises graduate students, postdoctoral researchers, and collaborators across chemistry, biology, and biomedical engineering departments.
