Rita Businaro

Rita Businaro is a Full Professor at the Department of Medical-Surgical Sciences and Biotechnologies at Sapienza University of Rome. With extensive research experience in neuroscience and molecular biology, she focuses on neurodegenerative diseases, particularly Alzheimer's disease, and explores innovative therapeutic approaches including nutraceuticals and oxygen-ozone therapy.

Her research interests span multiple interconnected fields including neuroinflammation, oxidative stress, autophagy mechanisms, and the endocannabinoid system. Dr. Businaro has made significant contributions to understanding how bioactive compounds from ancient wheat varieties like 'Senatore Cappelli' can exert anti-inflammatory and antioxidant effects, particularly in neurodegenerative contexts. Her work on oxygen-ozone therapy has examined its hormetic activity and potential clinical applications.

Her recent publications reveal a strong focus on the interplay between diet, neuroinflammation, and neurodegenerative diseases, with particular attention to how nutraceutical compounds can modulate microglial activation and autophagy pathways. The research demonstrates a consistent pattern of investigating how natural compounds and therapeutic approaches can counteract pathological mechanisms in Alzheimer's disease and related conditions.

Dr. Businaro leads the Laboratory of Neuromorphology and Stress-Related Pathologies and has been involved in several significant research projects including 'Role of endocannabinoids modulation in autophagy and inflammatory mechanisms underlying Alzheimer's disease,' 'FAAH targeting and endocannabinoids: impact on Alzheimer's disease,' and 'Non-pharmacological treatment of Alzheimer disease: the dietary impact.'

She teaches anatomy lessons for Medicine and Surgery programs and holds regular office hours on Wednesdays from 1:00pm to 3:00pm. Her work bridges basic science with potential clinical applications, particularly in the fields of neurodegeneration and inflammation-related pathologies.