Reuven Agami

Prof. Reuven Agami is a Full Professor in the Department of Molecular Genetics at Erasmus MC, Rotterdam. His research focuses on molecular mechanisms underlying cancer biology, particularly aberrant protein production and its therapeutic implications. Key areas include RNA translation regulation, immunotherapy targeting cancer-specific peptides, and mechanisms of therapy resistance in melanoma.

Research interests revolve around:

• Aberrant mRNA translation in cancer cells
• Mechanisms of ribosome stalling and DNA damage responses
• Adoptive T-cell therapies leveraging non-genetic cancer vulnerabilities
• Role of amino acid deprivation in therapeutic resistance

Recent articles highlight breakthroughs in understanding how cancer cells utilize non-genetic protein production heterogeneity, with implications for developing next-generation therapies. His work has been widely cited and covered in major scientific outlets.