Reinhard Friedrich

Reinhard Friedrich is a Professor at the University Medical Center Hamburg-Eppendorf (UKE) within the Clinic and Polyclinic for Oral, Maxillofacial and Facial Surgery. With over 40 years of clinical follow-up research, he specializes in complex oral and maxillofacial pathologies, particularly neurofibromatosis Type 1 (NF1)-related tumors, head and neck cancers, and genetic syndrome manifestations in craniofacial structures.

• Key research areas: Oral surgery, neurofibromatosis, stem cell applications, medical imaging, and biomarker development
• Active collaborations with UKE's Clinical Neuroimmunology and Head and Neck Oncology teams

Research Trends:
His recent 2025-2024 publications focus on three-dimensional anatomical analysis of cranial structures using CBCT, targeted therapies like selumetinib for neurofibromas, and stem cell optimization for tissue engineering. Earlier works include 30-year studies on spontaneous tumor regression and genetic screening in NF1 patients.

Notable Contributions:
• 40-year longitudinal study on facial neurofibroma treatment
• Pioneering use of Raman spectroscopy with AI in osteonecrosis analysis
• Development of scoring systems for dental and skeletal symmetry assessment