معرفی
Ravi S. Misra, Ph.D., serves as an Assistant Professor in the Department of Pediatrics at the University of Rochester School of Medicine and Dentistry, where he leads research on respiratory and immune system development in premature infants. His work bridges clinical neonatology and molecular biology through collaborative projects with physicians, nurses, and researchers across multiple disciplines.
- Ph.D. in Cell and Molecular Biology, University of Vermont, 2006
- B.S. in Biotechnology with Concentration in Biochemistry, Worcester Polytechnic Institute, 2000
Dr. Misra's research focuses on understanding how immune system and lung development alterations in preterm infants contribute to diseases like Bronchopulmonary Dysplasia (BPD), viral respiratory infections, and asthma-like conditions. He employs cutting-edge multi-omics methodologies to investigate inflammatory processes with the goal of developing targeted therapeutic interventions that could improve vaccine responses and treat inflammatory lung diseases in vulnerable infant populations.
His recent publications reveal a strong emphasis on multi-omics approaches to map lung development and disease mechanisms. Through leadership in the LungMAP and HuBMAP-Lung consortia, he has pioneered molecular atlases of human lung development while investigating immune dysregulation in preterm infants. Key themes include transcriptomic and proteomic signatures of lung maturation, neutrophil recruitment in respiratory infections, and inflammatory pathways in BPD pathogenesis.
Dr. Misra's scientific contributions have been recognized through multiple awards and fellowships:
- Recipient of Strong Star Award (2015)
- Respiratory Pathogens Research Center Innovation Award (2014)
- F32 Individual Fellowship (2008-2010)
- T32 Institutional Training Grants (2002-2008)
- Salisbury Prize and Provost's Award from WPI (2000)
As co-Investigator for the LungMAP program and Program Manager for HuBMAP-Lung, Dr. Misra directs significant NIH-funded research initiatives focused on creating comprehensive molecular maps of lung development. His collaborative approach integrates clinical data with advanced omics technologies to address critical gaps in understanding neonatal lung diseases.
Within the URMC Division of Neonatology, Dr. Misra collaborates with a multidisciplinary team including physicians, nurses, clinical coordinators, and biostatisticians. His laboratory contributes specialized expertise in primary human lung tissue processing and immune cell phenotyping, supporting both institutional research and national consortia efforts to decode the molecular basis of infant lung diseases.
