Rasmus Linser

Rasmus Linser is a Professor of Biomolecular NMR Spectroscopy at the Technical University of Dortmund, where he holds a W3 chair position in the Faculty of Chemistry and Chemical Biology, Department of Physical Chemistry. His research group develops and applies state-of-the-art NMR spectroscopic methods to investigate protein structure and dynamics, with particular expertise in both solid-state and solution NMR techniques. The Linser group is part of the Excellence Cluster RESOLV and the International Max-Planck Research School for Life Sciences.

Dr. Linser received his Diploma in Chemistry from the University of Göttingen and Universidad Autónoma de Madrid in 2006, followed by a PhD at the Leibniz Institute for Molecular Pharmacology in Berlin. His academic journey included research positions at UNSW Sydney, Harvard Medical School, and the Max Planck Institute for Biophysical Chemistry before his appointment as W2 Professor at LMU Munich (2016-2019) and subsequently as W3 Professor at TU Dortmund (2019-present).

Linser's research focuses on innovative elucidation of protein structure, dynamics, and function using NMR spectroscopy. His group has pioneered methods in proton-detected solid-state NMR, particularly for studying proteins without deuteration. Current research areas include protein conformational dynamics, membrane proteins, epigenetic readers, and methodological advances in high-dimensional NMR. The group maintains two high-field (700 and 800 MHz) Bruker spectrometers in their newly established laboratory in the CCB building at TU Dortmund.

The Linser group's recent publications demonstrate significant contributions to understanding protein dynamics, allosteric regulation, epigenetic mechanisms, and NMR methodology development. Their work spans structural biology, biophysics, epigenetics, and materials science, with particular emphasis on how protein dynamics govern biological function. The group has developed innovative approaches for studying large proteins and membrane systems using advanced NMR techniques.

Scientific Awards and Recognition:

• ERC Consolidator grant 'bypassNMR' (2023)
• Internationalization Award of TU Dortmund (2024)
• Felix Bloch Lecture Award for excellence in NMR spectroscopy (2015)
• Emmy Noether funding from the German Research Foundation
• Discovery Early Career Research Award from the Australian Research Council
• Liebig fellowship from the Association of the Chemical Industries

Professor Linser serves on the Executive Committee of the Experimental NMR Conference (ENC) and is actively involved in mentoring PhD students and postdoctoral researchers. His group has successfully guided multiple students to completion of their doctoral theses, with publications in high-impact journals including Nature Communications, Nucleic Acids Research, Angewandte Chemie, and PNAS. Current research is supported by multiple grants including the ERC Consolidator grant, DFG SFB 1309, and membership in the Excellence Cluster RESOLV.

The Linser laboratory maintains strong collaborations with the Max Planck Institute for Molecular Physiology and participates in the International Max-Planck Research School for Chemical and Molecular Biology. The group's facilities include state-of-the-art NMR instrumentation and protein expression/purification capabilities, enabling comprehensive structural and dynamic studies of biological macromolecules.