Radu O. Minea

Radu O. Minea is an Assistant Professor of Research in Neurological Surgery at the University of Southern California (USC). His research focuses on developing conjugated drug therapies for cancers such as glioblastoma, leukemia, and lymphoma. He specializes in preclinical models to evaluate the efficacy of novel compounds like NEO212, NEO214, and NEO100, which target cancer cells through mechanisms including autophagy inhibition, macrophage differentiation, and enhanced drug delivery to tumor sites. His work bridges molecular oncology, drug design, and translational medicine, with a particular emphasis on overcoming drug resistance in malignant tumors.

Key research areas include:

• Design and testing of conjugated chemotherapeutic agents
• Mechanisms of drug resistance in gliomas and hematologic malignancies
• Targeted drug delivery strategies for brain-localized cancers
• Role of disintegrins and venom-derived peptides in cancer therapy

Dr. Minea’s publications highlight innovations in radiosensitization, antiviral cancer therapies, and the application of multi-integrin targeting proteins. His research has implications for improving treatment outcomes in aggressive cancers like glioblastoma and acute myeloid leukemia.