REBECA GARCIA FANDIÑO

Rebeca García Fandiño is a Professor at the University of Santiago de Compostela, affiliated with the Department of Organic Chemistry within the Faculty of Biology. She is part of the Research Center in Biological Chemistry and Molecular Materials (CIQUS) and the SupraNanoBioMol research group, focusing on supramolecular systems and nanobiomimetics. Her doctoral work (2006) involved the synthesis of taxosteroids via metathesis reactions and theoretical studies of cyclization reactions. Key research areas include molecular dynamics simulations of lipid membranes, antimicrobial peptides, cyclodextrin-based drug delivery systems, and cyclic peptide nanotubes. Notable contributions include the Cyclo-lib database for cyclodextrin simulations and studies on cyclodextrin dimers for therapeutic oxysterol removal. Her work often integrates experimental and computational methods to explore membrane interactions, peptide assembly, and water models in confined systems. She has collaborated on projects addressing atherosclerosis treatment, drug design, and protein delivery mechanisms.

Education:

• PhD in Organic Chemistry, University of Santiago de Compostela (2006)

Research Interests:

• Supramolecular Chemistry and Membrane Biology
• Peptide Nanotubes and Drug Delivery Systems
• Cyclodextrin Applications in Therapeutics
• Molecular Dynamics Simulations of Biomembranes

Key Projects:

• Development of therapeutic cyclodextrin dimers for atherosclerosis treatment
• Investigation of cyclic peptide membrane interactions and antimicrobial mechanisms
• Creation of Cyclo-lib database for cyclodextrin molecular dynamics
• Studies on water models in transmembrane peptide nanotubes

Grants and Collaboration:

• Extensive funding for computational and experimental studies on biomimetic systems
• Interdisciplinary work combining chemistry, biology, and materials science

Labs and Affiliations: Active in CIQUS and SupraNanoBioMol, collaborating with institutions like the University of Helsinki and the National Research Council of Italy.