معرفی
Qiaolin Deng is an Associate Professor and Principal Researcher at the Department of Physiology and Pharmacology, Karolinska Institutet, Sweden. Her research group focuses on germ cell biology and developmental programming in epigenetic inheritance of diseases, particularly addressing how maternal health conditions like polycystic ovary syndrome (PCOS) and diabetes impact offspring health through placental and germline mechanisms.
Her research integrates mouse disease models, human stem cell cultures (including induced pluripotent stem cells and placental organoids), single-cell sequencing (Smart-seq2, LCM-seq), and microfluidic co-culture systems to investigate molecular pathways in developmental programming. Key themes include epigenetic remodeling, X-chromosome dosage effects, and modeling of maternal disease signatures in offspring.
Recent publications highlight her work on PCOS transgenerational effects, placental gene regulation, diabetes-related germline modifications, and advanced single-cell methodologies. She has secured prestigious grants including the Wallenberg Academy Fellow Grant, VR Consolidator Grant, and KIRI Fellow Grant, reflecting significant recognition in developmental biology and metabolic-reproductive medicine.
Scientific Awards:
- KI Research Incubator (KIRI) Fellow postdoc grant (2022)
- Wallenberg Academy Fellow Grant (2019)
- Karolinska Institutet Consolidator Grant
- Swedish Research Council (VR) Consolidator Grant
- Young Investigator grants from Swedish Society for Medical Research, Swedish Medical Research Council, and KI Central Faculty Fund
Her lab has trained numerous researchers, including PhD and master’s students, and collaborates with institutions such as UT Southwestern Medical Center, Tongji University, and Medical University of Vienna. Teaching contributions include EMBO courses on single-cell omics and advanced physiology lectures at Karolinska and Royal Institute of Technology.
