معرفی
Dr. Qiao-Hong Chen is a Professor in the Department of Chemistry and Biochemistry at California State University, Fresno. She holds dual affiliations with the College of Science and Mathematics and the Chen Research Group. Her career includes academic roles at Sichuan University (China, 2001–2012) and postdoctoral research at the University of Alberta (Canada) and Virginia Tech (USA).
Education: Ph.D. in Medicinal Chemistry (Sichuan University), M.S. and B.S. in Pharmacy (West China University of Medical Sciences).
Research Interests: Focuses on drug discovery for prostate cancer and oncology, including:
- Design of microtubule-stabilizing agents derived from macrolides
- Engineering curcumin and genistein analogs to enhance bioavailability
- Development of targeted therapies for castration-resistant prostate cancer
- Natural products chemistry and bioorganic medicinal chemistry
Publications: Over 164 peer-reviewed articles and 6 book chapters, with recent work emphasizing drug-protein interactions, novel anticancer agents, and structure-activity relationships. Key themes include protein degradation strategies (PROTACs), enzyme inhibition mechanisms, and drug delivery systems.
- 2017 Provost’s Research Award
- 2014 Natural Science Award (China Ministry of Education)
- 2003 Top 100 National Excellent Dissertation Award (China)
Grants & Advising: Extensive research funding history (details not explicitly listed). Mentored numerous graduate students through courses like Advanced Organic Chemistry and drug design seminars.
Labs/Teams: Leads the Chen Research Group, collaborating on projects involving medicinal chemistry, drug synthesis, and cancer biology.
