Pratip K. Bhattacharya

Pratip K. Bhattacharya, Ph.D., is an Associate Professor in the Department of Cancer Systems Imaging and the Department of Imaging Physics at The University of Texas MD Anderson Cancer Center, with a joint appointment in the Graduate School of Biomedical Sciences at The University of Texas Health Science Center. He is a principal investigator leading the Bhattacharya Laboratory, dedicated to advancing magnetic resonance imaging (MRI) through hyperpolarization techniques for applications in cancer and cardiovascular diseases.

His research focuses on developing real-time metabolic and molecular imaging methods using hyperpolarized ¹³C and ¹⁵N-labeled compounds and silicon nanoparticles. These innovative probes significantly enhance MRI sensitivity, enabling non-invasive assessment of tissue metabolism and targeted imaging. His lab's work spans three primary areas: real-time metabolic MR imaging, targeted molecular MR imaging with functionalized silicon nanoparticles, and high-resolution MR metabolomics. These efforts are aimed at improving disease diagnosis and therapy monitoring.

Analysis of his recent publications reveals a strong and consistent focus on hyperpolarized MRI, particularly using silicon particles and metabolic tracers like succinate, to visualize cancer metabolism and cardiovascular conditions in vivo. His research integrates physics, chemistry, and biomedical engineering to create novel imaging tools with direct clinical translational potential.

• PHIP Hyperpolarization
• Dynamic Nuclear Polarization (DNP)
• Hyperpolarized Silicon Nanoparticles
• Real-Time Metabolic Imaging
• Cancer and Cardiovascular Imaging
• Theranostic Applications

Dr. Bhattacharya actively mentors graduate students and postdoctoral fellows, including Saleh Ramezani, Jose Enriquez, Dontrey Bourgeois, and Kang-Lin Hsieh. He collaborates closely with physician-scientists, radiologists, and oncologists to ensure his imaging science innovations address critical clinical needs. His laboratory is supported by grant funding, facilitating the development of cutting-edge imaging technologies.

The Bhattacharya Laboratory is a key component of the Division of Diagnostic Imaging at MD Anderson, fostering a collaborative environment for interdisciplinary research. The lab focuses on translating fundamental discoveries in hyperpolarization physics into practical tools for improving cancer care.