معرفی
Pier Luigi Martelli is a Full Professor in the Department of Pharmacy and Biotechnology at the University of Bologna. His research focuses on computational biology, bioinformatics, and protein structure prediction, with a particular emphasis on integrating machine learning into biological problem-solving. He leads the Bologna Biocomputing Group, developing web-based tools like Alpha&esmhfolds for protein model comparison and ISPRED-SEQ for interaction site prediction.
Key research areas include:
- Protein stability and variant effect prediction (via CAGI challenges)
- Genomic and proteomic analysis of pathogens (e.g., Brucella spp., termite genomes)
- Development of bioinformatics databases (e.g., MultifacetedProtDB)
- Applications of quantum computing in biology
His work bridges computational methods with experimental biology, addressing problems in enzyme function, disease-associated variants, and structural biology. Recent projects include evaluating AlphaFold2/ESMFold models and exploring the resistome in livestock systems.
