معرفی
Pia Vahteristo serves as a University Researcher at the University of Helsinki's Faculty of Medicine within the Department of Medical Genetics and Inherited Medicine. She leads the ATG - Applied Tumor Genomics research group and supervises doctoral candidates in the Biomedicine Programme.
Her research centers on genomic mechanisms of gynecological disorders, particularly uterine leiomyomas and endometriosis. Using whole-genome and exome sequencing, she identifies molecular subtypes, chromosomal rearrangements (HMGA2/HMGA1/PLAG1), and driver mutations (MED12, NRF2 pathway). Current work focuses on translating genomic findings into clinical risk prediction models and personalized intervention strategies.
Recent publications (2022-2025) reveal consistent genomic investigation of uterine tumors, with emerging themes in MED12 mutation impacts, surgical outcome correlations, and novel pathways like Cullin-3 neddylation defects. Her work bridges basic tumor genomics with clinical gynecology through multi-institutional collaborations.
Dr. Vahteristo currently directs two major funded projects: the JAES initiative (2025-2028; €500,000 from Jane and Aatos Erkko Foundation) exploring tumor evolution, and a Cancer Foundation project (2023-2025; €120,000) investigating endometriosis genetics. As doctoral supervisor, she mentors next-generation researchers in genomic medicine.
She operates within the ATG - Applied Tumor Genomics team, which specializes in integrating archival tissue analysis with cutting-edge sequencing technologies to decode gynecological tumor biology and improve diagnostic frameworks.
