معرفی
Petr Cejka is a Full Professor at the Università della Svizzera italiana (USI) and a Group Leader at the Institute for Research in Biomedicine (IRB) in Bellinzona, Switzerland. He leads the Recombination Mechanisms research group, focusing on DNA repair and genome stability.
His research interests lie at the intersection of molecular biology and genetics, particularly in DNA double-strand break repair, homologous recombination, and replication fork stability. His work employs biochemical, genetic, and structural approaches to dissect the mechanisms of key repair proteins such as MRE11, CtIP, EXO1, and BRCA1. He has made seminal contributions to understanding the initiation of DNA end resection and the regulation of meiotic recombination.
His recent publications reveal a strong trend in exploring the molecular mechanisms of DNA repair pathways, especially in the context of cancer biology and genome editing. Articles such as 'Mechanism of BRCA1-BARD1 function' and 'Comprehensive interrogation of synthetic lethality' highlight his focus on DNA damage response and therapeutic implications. His work increasingly integrates structural insights and single-molecule techniques.
- Dr. Ernst Th. Jucker Award (2015)
- Friedrich Miescher Award (2017)
- San Salvatore Award (2024)
- ERC Consolidator Grant (2016)
- ERC Advanced Grant (2021)
- EMBO Member (since 2021)
Cejka advises a team of postdoctoral researchers and students, fostering a collaborative research environment. His lab has received continuous funding from the European Research Council and the Swiss National Science Foundation. He actively collaborates with international research groups, including those at Rockefeller University. His lab is involved in antibody discovery and participates in European research networks.
