Per Hansson

Per Hansson is a Professor at Uppsala University in the Department of Medicinal Chemistry; Pharmaceutical Physical Chemistry. His research focuses on pharmaceutical physical chemistry with emphasis on drug delivery systems, particularly hydrogels and microgels for controlled drug release applications. His laboratory is based at the Biomedical Center (BMC) in Uppsala, where he conducts research at the intersection of polymer science, physical chemistry, and pharmaceutical technology.

Professor Hansson's research program centers on developing and characterizing advanced drug delivery systems that address key challenges in pharmaceutical formulation. His primary focus involves understanding the physical chemistry of drug-polymer interactions, particularly in polyelectrolyte systems. He has pioneered the use of small-angle and ultra small-angle X-ray scattering techniques to characterize pharmaceutical materials at the nanoscale. His work on hydrogels that mimic subcutaneous interstitial space has created more predictive models for studying peptide drug delivery. He has also developed innovative microfluidic platforms for investigating drug release mechanisms and peptide-polymer interactions. His research spans from fundamental studies of phase behavior in polymer-drug systems to applied research on specific delivery platforms for anticancer drugs and antidepressants.

Analysis of Professor Hansson's recent publications (2020-2025) reveals a strategic evolution toward increasingly complex biomimetic systems and sophisticated characterization techniques. His current work demonstrates a strong emphasis on creating physiologically relevant models for subcutaneous drug delivery, with particular attention to peptide therapeutics. He has successfully integrated multiple advanced methodologies including X-ray scattering, FRAP analysis, and microfluidics to create a comprehensive understanding of drug transport and release mechanisms in complex biomimetic environments. His publications consistently address both fundamental physical chemistry questions and their practical pharmaceutical applications.

Professor Hansson has made significant contributions to understanding how drug properties influence loading and release from microgel carriers, with particular insights into amphiphilic drugs and peptide therapeutics. His theoretical models of phase behavior in polyelectrolyte gels have advanced the field's understanding of responsive drug delivery systems. His work on drug-eluting beads has provided valuable insights into controlled release mechanisms for clinical applications.