معرفی
Professor Payam Gammage is a leading researcher in Mitochondrial Oncogenetics at the University of Glasgow's School of Cancer Sciences and Cancer Research UK Scotland Institute. His work bridges mitochondrial genetics, cancer metabolism, and tumor microenvironment dynamics.
Education:
- PhD in Biochemistry, University of Cambridge (2015)
- MSc in Neuroscience, University College London (2011)
Research Focus:
Payam investigates how mitochondrial DNA (mtDNA) mutations contribute to cancer progression through metabolic reprogramming and mitochondrial-nuclear genome interactions. His lab explores oxidative phosphorylation impairment, aerobic glycolysis, and immunotherapy response in solid tumors.
Scientific Trends:
Recent publications highlight mtDNA's role in immunotherapy efficacy, single-cell mtDNA dynamics, and therapeutic strategies for heteroplasmy. Key subfields include mitochondrial gene expression, metabolic adaptation, and mitochondrial DNA editing tools.
Honors:
- EMBO Young Investigator (2024-2027)
- National Institutes of Health MERIT Award (2022)
- ERC Starting Grant (2021)
Advising & Collaborations:
He mentors PhD student Flora McNulty and Masters student Amy Shepherd. His lab includes postdoctoral scientists and research associates working on pancreatic cancer, colorectal cancer, and mitochondrial reprogramming in tumors.
