معرفی
Pawel Swietach is a Professor of Physiology in the Department of Physiology, Anatomy and Genetics (DPAG) at the University of Oxford, where he leads the Swietach Research Group. He is affiliated with Corpus Christi College and his work is primarily supported by the European Research Council (ERC) and the British Heart Foundation (BHF).
Professor Swietach's research centers on how biological processes are affected by chemical acidity (pH), with two main pillars: cardiac biology and cancer. His lab investigates how acidity influences cardiac diseases and tumor progression, seeking mechanisms that could lead to better diagnosis and treatment. His work reveals how pH changes affect cellular signaling, metabolic processes, and disease mechanisms in both cardiovascular and oncological contexts.
Analysis of his recent publications shows a consistent focus on pH signaling across multiple biological systems. His work spans cardiac physiology, cancer metabolism, oxygen transport, and endocrine regulation, demonstrating how acidity serves as a fundamental regulator across diverse physiological processes. The research combines molecular, cellular, and systems approaches to understand how pH affects biological function in health and disease.
His significant scientific achievements include:
- Royal Society University Research Fellowship (2008)
- ERC Consolidator Award (2017)
- Member of the Academia Europeae (2024)
Professor Swietach leads a BHF Programme on acidity in hypertrophic cardiac growth and has secured substantial funding from the ERC. His research program spans multiple collaborative projects including the EU consortium IONTRAC. His work bridges basic science with potential clinical applications in cardiovascular disease and cancer.
He leads the Swietach Research Group within DPAG and is involved with the Boyman Group. His laboratory investigates pH signaling mechanisms using advanced techniques in molecular physiology, cellular imaging, and systems biology to understand how acidity affects cellular function in both normal physiology and disease states.