Pauline Themans

Pauline Themans is a Research Fellow at the University of Namur, Faculty of Science, Department of Mathematics. She is affiliated with the naXys Research group (Namur Institute of Complex Systems) and specializes in applying control systems theory to pharmacokinetic modeling and drug dosing optimization. Her work bridges mathematics, pharmacology, and clinical medicine to develop personalized treatment approaches.

Her research interests focus on pharmacokinetics and the application of control theory to drug dosing systems. Themans develops mathematical models for antibiotic dosing optimization and has made significant contributions to understanding drug pharmacokinetics in special populations, including COVID-19 patients. Her work integrates systems theory with clinical pharmacology to create model-informed dosing strategies that account for individual patient characteristics.

Analysis of her publication trends reveals a strong focus on translating control systems theory into practical clinical applications, particularly for antibiotic therapy and COVID-19 treatment. Her research demonstrates how mathematical modeling can address complex pharmacokinetic challenges in diverse patient populations, with an emphasis on dose optimization for improved therapeutic outcomes.

Themans has been actively involved in academic collaborations, presenting her work at numerous conferences including the 39th Benelux meeting on Systems and Control (2020) and the naXys Research Day (2019). Her research outputs demonstrate consistent productivity with 14 publications documented between 2017-2022, including journal articles, book chapters, and conference contributions.

Her doctoral thesis titled 'Pharmacokinetic modeling and control design for drug dosing' was completed in July 2021 under the supervision of WINKIN, J. and Musuamba Tshinanu, F. Prior to this, she completed a Master's thesis in Mathematics in June 2015 titled 'Modélisation, analyse et contrôle de systèmes pharmacocinétiques : application au méropénem'.