Paul J. Fletcher

Dr. Paul J. Fletcher is a Professor of Psychology at the University of Toronto and holds a senior research position at the Centre for Addiction & Mental Health (CAMH). As Senior Scientist and Head of Biopsychology in the Campbell Family Mental Health Research Institute, he leads investigations into the neurochemical foundations of addiction and psychiatric disorders.

• Research Focus: Roles of serotonin receptor subtypes (5-HT2A, 5-HT2C) in addiction and impulsivity
• Key Findings: 5-HT2C receptor activation reduces cocaine reinforcement, while D1 agonists reverse cognitive deficits in schizophrenia models
• Collaboration: Work with Dr. Guy Higgins (NPS Pharmaceuticals) on serotonin depletion studies