Paul Dutchak

Paul Dutchak is an Assistant Professor at the Department of Psychiatry and Neuroscience, Faculty of Medicine, Laval University. His research focuses on neurometabolic pathways in brain health and disease, particularly epilepsy, autism, and tuberous sclerosis. He investigates how genetic mutations affect metabolic regulation via complexes like GATOR1 and mTORC1.

• B.Sc., M.Sc.: University of Saskatchewan, Biochemistry
• Ph.D.: University of Texas Southwestern Medical Center

Dr. Dutchak’s work maps metabolic dysregulation in neurological disorders, exploring mechanisms like:

• mTORC1 signaling in neuronal function
• GATOR1 complex mutations linked to epilepsy
• Metabolic-epigenetic interactions in neurodegeneration
• RNA granule dynamics in ALS/FTD

Recent publications highlight collaborations across neuroscience, molecular biology, and metabolic research. His lab develops therapeutic strategies targeting metabolic regulators like GRN mRNA and NPRL2.

Scientific awards include:

• Brain Canada Future Leaders Award (2023–25)
• NSERC Discovery Grant (2018–25)
• FRQS Junior 1 Award (2020–24)

Dr. Dutchak mentors graduate students and postdocs, with team members like Maéline Muller and Chantelle Sephton. His work intersects metabolism, neurodegeneration, and translational neuroscience.