Patrick Öckl

Patrick Öckl is a researcher at the Center for Biomedical Research, Ulm University, specializing in biomarker discovery for neurodegenerative diseases. His work focuses on amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), aligning with the research priorities of the German Center for Neurodegenerative Diseases (DZNE) Ulm site.

• Key research methods: mass spectrometry (LC-MS/MS, MRM, PRM), immunoassays (Simoa, ELLA)
• Clinical applications: biomarker validation in cerebrospinal fluid, serum, and plasma
• Current projects: characterization of proteins like UCHL1, MAP2, GPNMB, and NPTXR as potential biomarkers

His group employs cutting-edge technologies including Thermo Exploris 480 Orbitrap and Sciex QTRAP6500 systems for proteomic and peptidomic studies. Research outcomes aim to improve early diagnosis, differential diagnosis, and monitoring of neurodegenerative diseases through translational approaches.