Pamela England

Pamela England is a Professor in the Department of Pharmaceutical Chemistry at the University of California, San Francisco (UCSF), with a joint appointment in the Department of Cellular and Molecular Pharmacology, School of Medicine. Her research focuses on developing chemical probes to study signaling proteins involved in synaptic transmission and gene transcription, targeting glutamate-gated ion channels and nuclear receptors. England holds a PhD in Chemistry from MIT and has held postdoctoral positions at Caltech and Stanford. She is affiliated with the Quantitative Biosciences Institute (QBI) and multiple graduate programs including Biophysics and Neuroscience.

Research Interests:

• Design of small molecules to manipulate nuclear receptors (e.g., Nurr1, LRH1) for neurodegenerative disease research
• Development of chemical tools to study glutamate receptor dynamics in synaptic plasticity
• Integration of synthetic chemistry, structural biology, and computational methods for drug discovery

Honors & Awards:

• Multiple Dean’s Awards for Excellence in Teaching (2018–2021)
• McKnight Technological Innovations in Neuroscience Award (2006)
• Grass Foundation Fellowship (1998)

Grants & Lab:

• Principal Investigator on NIH grants studying nuclear receptor modulators and synaptic receptors
• England Lab investigates Parkinson’s disease mechanisms via ligand-receptor systems