معرفی
Ozlem Keskin is a Professor in the Department of Chemical and Biological Engineering at Koc University, where she also serves as Associate Dean of the College of Engineering and Director of the Graduate School of Sciences & Engineering. Her research focuses on bioinformatics and computational biology, particularly protein-protein interactions and the human interactome. She leads a TUBITAK-funded project constructing the human interactome and develops algorithms for 3D modeling of cellular interactions.
Her laboratory (Cosbi Lab) specializes in computational approaches to protein interactions, structural bioinformatics, and drug discovery. Research interests include protein interaction networks, structural coverage of the human interactome, conformational diversity in signaling pathways, and applications in neurodegenerative and cardiovascular diseases. She applies machine learning techniques to problems in protein interface prediction and validation.
Recent publications (2023-2025) demonstrate extensive work on protein-protein interfaces, viral-host interactions, cancer signaling pathways, and microbiome alterations. Her team develops computational resources like PPInterface and DiPPI datasets and creates methods such as DeepAllo for allosteric site prediction. She maintains collaborations with clinical researchers on immunodeficiencies, neurodegenerative disorders, and women's health.
