Owen N. Witte

Owen N. Witte is a Professor at the David Geffen School of Medicine, University of California Los Angeles (UCLA), with dual appointments in Microbiology, Immunology & Molecular Genetics and Molecular and Medical Pharmacology. His research focuses on prostate cancer, neuroendocrine cancer, T cell receptor engineering, and molecular pharmacology.

Research Highlights:

• Identified PGC-1α's role in neuroendocrine cancer progression
• Developed nanovial-based TCR screening for cancer immunopeptidomics
• Explored MYC-dependent RNA splicing in prostate cancer
• Mapped genomic/epigenomic landscapes of aggressive prostate cancer

Scientific Awards:

• NIH U01CA233074
• NIH R01CA222877
• NIH R01CA220238
• NIH U01CA164188

Collaborative Work includes immunotherapy development, cancer stem cell characterization, and precision medicine strategies for lethal neuroendocrine prostate cancer.