معرفی
Owais Khan serves as an Assistant Professor in the Department of Biomedical Engineering at Toronto Metropolitan University, where he leads research in cardiovascular biomechanics to improve heart disease diagnosis and treatment through engineering-driven approaches combining computational simulations, medical imaging, and biomechanics.
His research program focuses on three interconnected pillars: developing physics-based computational models for blood flow simulation in patient-specific anatomies; advancing medical imaging techniques like dynamic CT myocardial perfusion and vessel wall MRI for quantitative physiological assessment; and conducting fundamental biomechanics studies to optimize prosthetic valve designs. This work directly addresses critical clinical challenges including heart surgery complications, aneurysm rupture prediction, and vein graft failure in coronary bypass patients.
Khan's publication record demonstrates consistent innovation in cardiovascular computational modeling, with recent work emphasizing personalized medicine through physics-informed neural networks, multi-fidelity uncertainty quantification, and integration of CT perfusion imaging for coronary hemodynamics. His research bridges engineering principles with clinical cardiology to enable virtual treatment planning and risk stratification without additional patient risk.
His scientific contributions have been recognized with prestigious awards including the American Heart Association Postdoctoral Fellowship, NSERC Postdoctoral Fellowship, Baxter Young Investigator Award, and MITACS Globalink Research Award.
As director of the Cardiovascular Imaging and Modeling Biomechanics Lab (CIMBL), Khan maintains active collaborations with clinicians and radiologists at major hospitals, facilitating direct translation of engineering solutions to clinical cardiovascular medicine through a multi-disciplinary approach focused on personalized treatment strategies.
