Oumeng Zhang

Oumeng Zhang serves as a Postdoctoral Scholar Research Associate in Electrical Engineering at the California Institute of Technology, working under Professor Changhuei Yang in the renowned Biophotonics Laboratory. As a Resnick Postdoctoral Scholar, Zhang contributes to cutting-edge research at the intersection of optics, computation, and biomedical applications.

Zhang's research interests span multiple advanced imaging domains including biophotonics, computational microscopy, optical imaging, wavefront engineering, Fourier ptychography, non-line-of-sight imaging, and AI applications in medical imaging. The work focuses on developing novel tools that combine optics and microfluidics to tackle diagnostic and measurement problems in biology and medicine, with particular emphasis on pushing the performance of standard microscopes beyond their physical limitations through computational approaches.

Analysis of Zhang's recent publications reveals a strong trend toward increasingly sophisticated computational imaging techniques that integrate artificial intelligence with advanced optical methods. The research demonstrates a progression from fundamental optical principles to complex multi-dimensional imaging systems capable of capturing molecular orientation, volumetric structures, and dynamic biological processes with unprecedented resolution. Key thematic areas include polarization imaging, quantitative phase retrieval, neural network-enhanced reconstruction, and multi-view optical systems that achieve isotropic resolution.

• Resnick Postdoctoral Scholar fellowship

Zhang's research is supported through the Resnick Sustainability Institute fellowship and contributes to the broader research portfolio of the Biophotonics Laboratory, which receives funding from multiple federal agencies and private foundations supporting innovative biomedical imaging technologies. The laboratory environment fosters interdisciplinary collaboration between electrical engineers, biologists, and computer scientists working toward transformative diagnostic tools.

The research takes place within Caltech's Biophotonics Laboratory, which specializes in developing novel optical tools that combine optics and microfluidics to tackle diagnostic challenges in biology and medicine. Major projects include Fourier Ptychographic microscopy, time-reversal optical focusing, and parallel microscopy systems that transform physical optical problems into computational challenges.