Nolan Hoffman

Dr. Nolan Hoffman is a Senior Lecturer at Australian Catholic University (ACU) within the Centre for Human Performance & Metabolism at the Mary MacKillop Institute for Health Research, Melbourne campus. An integrative physiologist, he supervises PhD students and teaches human biological sciences while leading research on exercise-metabolism interactions.

His educational background includes:

• BSc with Honours in Biology from Butler University (2007)
• PhD in Cellular and Integrative Physiology from Indiana University (2012)

Hoffman's research employs human, animal, and cellular models to investigate molecular networks of exercise and metabolic control. Key foci include:

• AMPK biology and glycogen metabolism in energy sensing
• Exercise signaling networks via phosphoproteomics and metabolomics
• Mechanisms underlying insulin resistance and type 2 diabetes

His publication trends (2012-2025) demonstrate consistent innovation in exercise biochemistry, with recent work on HIIT signaling, ACL injury rehabilitation, and mitochondrial networks using multi-omics approaches.

Scientific recognition includes:

• Australian Physiological Society Postdoctoral Publication Prize (2015)
• Garvan Institute Best Poster Award (2013)
• IUPUI Chancellor’s Scholar (2012)

As a full HDR Supervisor, he leads multiple PhD projects and has secured A$650k+ in grants including an ARC Discovery Project (A$493k) on mitochondrial biogenesis and a Defence Science Institute grant on ACL injury. His editorial roles span Frontiers in Endocrinology and Asian Journal of Kinesiology, with extensive peer review for top journals including Cell Metabolism and Nature Communications.

Hoffman collaborates through ACU's Centre for Human Performance & Metabolism and St Vincent's Institute of Medical Research, utilizing multidisciplinary teams for translational exercise physiology research.