Noah Connally

Noah Connally, Ph.D., is a Research Fellow in Biomedical Informatics at Harvard Medical School's Department of Biomedical Informatics. He is affiliated with the O'Connor Lab and conducts research under the joint supervision of Luke O'Connor and Elinor Karlsson. Dr. Connally received his Ph.D. from Harvard Medical School where he trained in Shamil Sunyaev's laboratory.

His research focuses on comparative and evolutionary approaches to complex trait genetics, with emphasis on:

• Genetic mapping of autoimmune diseases
• Regulatory mechanisms in hypercholesterolemia
• Functional links between genetic associations and disease phenotypes
• Evolutionary genetics of complex traits

Recent publications (2022-2025) demonstrate his work in identifying regulatory mechanisms for hypercholesterolemia genes, mapping shared genetic associations across autoimmune disorders, and bridging genetic associations with regulatory functions. His research employs computational genomics and large-scale genetic analyses to uncover fundamental disease mechanisms.

Dr. Connally collaborates extensively with researchers at Harvard Medical School and participates in multi-institutional consortia including the International Multiple Sclerosis Genetics Consortium. His work connects genetic discoveries with clinical insights in cardiovascular and autoimmune diseases.