معرفی
Nils Eiel Steen is a researcher affiliated with institutions involved in psychiatric and neurobiological research, focusing on severe mental illnesses such as schizophrenia and bipolar disorder. His work explores the interplay between
- Inflammatory and immune markers
- Neurodevelopmental and neurodegenerative mechanisms
- Cardiovascular risk factors
- Neurotransmitter signaling pathways (Notch, Wnt)
- Infectious agents and mental health
Research areas include neuroimmunology, biological psychiatry, and systems biology of mental disorders. Publications reveal collaborations with leading researchers in Scandinavian institutions, emphasizing biomarker discovery and longitudinal analyses of immune-cognitive subgroups.
Key findings from his work:
- IL-18 links to agitation in severe mental disorders
- Notch/Wnt signaling disruptions in schizophrenia/bipolar disorder
- Adiponectin's role in cardiovascular risk independent of antipsychotics
- Genetic overlaps between cortical brain structure and immune markers
- Neurodegeneration markers like NSE in SMI
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