Nelson Shu-Sang S. Yee

Nelson Shu-Sang S. Yee is an Associate Professor of Medicine at Penn State College of Medicine, where he leads the Gastrointestinal Oncology research program. He specializes in diagnosing and treating cancers of the digestive system, including pancreatic, hepatocellular, and gastrointestinal malignancies.

• Education
  • Dual B.S. in Pharmacy and Chemistry (Summa Cum Laude, Valedictorian) at Massachusetts College of Pharmacy
  • MD and PhD in Molecular Biology at Weill Cornell Medical College and Memorial Sloan Kettering Cancer Center
  • Clinical training in Internal Medicine, Hematology, and Medical Oncology at Hospital of University of Pennsylvania

Dr. Yee's research focuses on predictive biomarkers and novel therapies for digestive organ cancers. He has published over 83 research outputs, including studies on pancreatic cancer, immune-related genes, and precision oncology, with recent work analyzing granzymes in tumor microenvironments and cell-free RNA as metabolic disease biomarkers.

His publications demonstrate expertise in:

• Cancer biology (e.g., pancreatic adenocarcinoma, hepatocellular carcinoma)
• Imaging and diagnostics (e.g., contrast-enhanced ultrasound, MRIs)
• Translational medicine (e.g., zebrafish models, chemotherapy response)

Scientific honors include:

• American Cancer Society Research Fellowship
• Eli Lilly Achievement Award
• National Institutes of Health Career Development Award

As an academic leader, Dr. Yee directs hematology/oncology educational programs and serves on editorial boards for journals such as Frontiers in Oncology and World Journal of Translational Medicine. He has secured grants from the National Institute of Diabetes and Digestive and Kidney Diseases for zebrafish pancreas development research.