Neera Tewari-Singh

Neera Tewari-Singh, PhD, is an Associate Professor in the Department of Pharmacology & Toxicology at Michigan State University, affiliated with the College of Osteopathic Medicine. Her research focuses on Environmental Toxicology, Drug Discovery, and Immunity/Inflammation, particularly addressing chemical warfare agents (e.g., sulfur mustard, phosgene oxime) and their effects on ocular and skin tissues. She investigates mechanisms of toxicity, biomarkers of injury, and therapeutic countermeasures.

Dr. Tewari-Singh holds grants from the National Institutes of Health (NIH) for studies on vesicant agents' ocular and systemic toxicity, including projects on chloropicrin and nitrogen mustard. Her work employs mouse and rabbit models to evaluate treatments like dexamethasone and silibinin. She leads a lab with staff (e.g., Steve Lundback) and postdocs (e.g., Ashten Stambersky), mentoring students in toxicology and pharmacology.

Her research spans

• Corneal injury mechanisms from vesicants,
• Systemic effects of dermal chemical exposures,
• Anti-inflammatory drug development,
• Mast cell and cytokine roles in toxicity,
• Metabolomics-based pathway analysis.

Publications highlight advancements in understanding phosgene oxime's urticant effects, chloropicrin-induced fibrosis, and sulfur mustard's ocular damage. Her lab's innovations include supersaturated oxygen emulsions for ocular trauma treatment.