معرفی
Dr. Nadia Ameen is a Professor of Pediatrics (Gastroenterology) and Cellular and Molecular Physiology at Yale University School of Medicine. As an NIH-funded physician-scientist with over two decades of laboratory leadership, she investigates mechanisms of diarrheal diseases with focus on CFTR chloride channel regulation in genetic and non-genetic intestinal disorders including Cystic Fibrosis. Her research spans trafficking mechanisms, kinase signaling pathways, and translational applications for drug therapies like Linaclotide and Lubiprostone.
- MBBS from University of West Indies (1985)
Her research program combines:
- CFTR trafficking regulation
- Microvillus Inclusion Disease (MVID) pathogenesis
- SGK1 kinase signaling effects
- Neuropod cell biology
- Translational organoid models
- Pediatric gut health promotion
Key contributions include:
- Discovery of CFTR trafficking mechanisms
- Identification of BEST4+ neuropod cells
- Development of humanized mouse models
- Elucidation of stress-induced signaling pathways
- Advancement of nutritional interventions for children
Scientific recognition includes the 2020 NASPGHAN Award for Study of Disorders Associated with Carbohydrate Malabsorption. She leads the Ameen Lab at The Anlyan Center (300 Cedar Street, New Haven) and participates in the Discovery to Cure Internship program.
