Mustafa Aziz Hatiboğlu

Professor Mustafa Aziz Hatiboğlu is a neurosurgeon and translational researcher at Bezmialem Vakif University Medical School, Turkey, where he directs the Gamma Knife Unit and leads the Brain Tumor Research Laboratory at BILSAB. His work bridges clinical neurosurgery with laboratory research, focusing on gliomas and brain metastases.

• Department of Neurosurgery, Bezmialem Vakif University
• Beykoz Institute of Life Sciences and Biotechnology (BILSAB)

Research Interests center on glioma and brain metastasis, with emphasis on:

• Radio- and chemo-resistance mechanisms
• Glioma cancer stem cells
• Immune regulation in tumor microenvironment
• Liquid biopsy for biomarker discovery
• Radiogenomics and tumor microbiome
• Advanced surgical techniques (awake craniotomy, intraoperative neuromonitoring)

The lab's research involves mouse glioma models, NOTCH signaling in chemoresistance, and circulating tumor cell isolation. Publications focus on autophagy, nanomedicine, and STAT3 inhibition in glioblastoma. Recent projects explore microbiome interactions and liposomal mRNA vaccines.

Scientific Awards include:

• Journal of Neuro-Oncology Award (2008 AANS Meeting)
• National Brain Tumor Society Mahaley Clinical Research Award (2010 CNS Meeting)

Teaching includes graduate courses in translational neurooncology and brain metastasis management. He supervises PhD students Büşra Karaçam and Berrin Saraçoğlu, among others.