Mu-Han Lin

Mu-Han Lin, Ph.D., is a Professor in the Department of Radiation Oncology at UT Southwestern Medical Center, with leadership roles including Senior Director of Clinical Physics and lead physicist for head and neck radiation oncology. Her academic profile spans Medical Physics, Adaptive Radiation Therapy, and Artificial Intelligence (AI) in Radiotherapy.

• Education: Master’s and Ph.D. in Medical Physics from National Tsing Hua University, Taiwan
• Training: Medical Physics Residency at Fox Chase Cancer Center, Philadelphia

Dr. Lin’s research focuses on online adaptive radiation therapy (oART) systems, particularly cone beam CT-guided workflows for gastric MALT lymphoma and head/neck cancers. She pioneered techniques for dose prediction, plan quality assurance, and deep learning integration to address anatomical variations during treatment. Her work demonstrates reduced PTV margins (0.5-0.7 cm) while maintaining target coverage and minimizing organ-at-risk (OAR) doses through auto-contouring and synthetic CT optimization.

Recent publications highlight her leadership in adaptive treatment planning (15+ articles from 2024-2025) across journals like Medical Physics, Practical Radiation Oncology, and Radiotherapy and Oncology. Key contributions include:

• X-Ray Guided Ethos Platform workflows
• Plan Quality Review Checklists
• HyperSight CBCT for image quality enhancement
• Inter-patient adaptive strategies for spine SAbR
• AI-driven segmentation and dose adaptation

She actively contributes to clinical education as an instructor in UT Southwestern’s Medical Physics Certificate Program and Biomedical Engineering Graduate Program, and chairs symposiums on X-ray Guided Adaptive RT. Dr. Lin serves on editorial boards for Therapeutic Radiation and Oncology and Medical Physics, and collaborates on grants with Varian Medical Systems and other industry partners.