Misty Good

Misty Good, MD, MS is an Associate Professor in the Department of Pediatrics at the University of North Carolina at Chapel Hill School of Medicine. Her research focuses on necrotizing enterocolitis (NEC) and neonatal intestinal biology, with over 100 publications in pediatrics, neonatology, and gastrointestinal disease.

• UNC Children's Hospital affiliation
• NIH-funded research program
• Director of multi-institutional NEC Biorepository

Research interests include:

• Cellular and molecular mechanisms of NEC pathogenesis
• TLR4 signaling in intestinal injury
• Human milk components and intestinal protection
• Microfluidic 'NEC-on-a-chip' technology
• Epigenetic regulation in neonatal intestines
• Immune cell dynamics in NEC

Recent publications highlight her work on:

• Microbiome alterations in NEC
• DNA methylation signatures as biomarkers
• Human enteroid culture systems
• TLR4 inhibition strategies
• Stool and urine proteomics for NEC diagnosis
• Stem cell-based intestinal repair

Her translational research bridges basic science with clinical implementation through:

• NEC Biorepository with 10,000+ samples
• Multi-institutional collaborations
• NIH grants for pediatric physician-scientist training
• Innovative animal models of neonatal disease
• Development of clinically relevant diagnostic tools
• Microfluidic organoid modeling