Mirela Sedić

Mirela Sedić, Ph.D. is a senior scientific associate at the Institute for Anthropological Research in Croatia, with extensive research experience in cancer biology and therapy. She has authored over 50 scientific publications in high-impact journals such as BBA Molecular Basis of Disease, Molecular Cancer, The Journal of Pathology, and others, with her work cited 1286 times (h-index 17; i10-index 30). Dr. Sedić serves as a reviewer for numerous international scientific journals and holds editorial board positions with Global Journal of Cancer Therapy, American Journal of Pharmacology & Therapeutics, Current Cancer Therapy Reviews, Clinical Cancer Drugs, and BMC Cancer.

Dr. Sedić's research spans multiple critical areas in oncology, with particular focus on gastrointestinal cancers including colon, liver, and pancreatic cancer. Her work investigates cancer cell signaling pathways, mechanisms of chemoresistance, and novel therapeutic approaches including drug repurposing and combination treatments. She employs advanced techniques such as mass spectrometry-based proteomics and lipidomics, combined with bioinformatics analysis, to dissect complex cancer biology phenomena.

Analysis of Dr. Sedić's recent publication record reveals a strong emphasis on understanding therapy resistance in BRAF-mutant colon cancer, with particular attention to sphingolipid metabolism pathways. Her research has increasingly incorporated multi-omics approaches to identify potential therapeutic targets and develop strategies to overcome resistance to targeted therapies like vemurafenib.

Dr. Sedić has received significant recognition through multiple scientific honors:

• International patent WO/2010/052510
• Appointment as expert evaluator for EU Framework Programs (FP7, HORIZON 2020, Horizon Europe) since 2012
• Editorial Board membership with five prominent cancer research journals

As a principal investigator, Dr. Sedić has secured competitive funding for multiple significant research projects, including a Croatian Science Foundation project (2019-2023), University of Rijeka research grants, and international collaborations with institutions like the Functional Genomics Center Zurich. Her consistent success in obtaining research funding demonstrates the significance and impact of her work in advancing our understanding of cancer biology and therapy.